Sleep, Self-Management, and Glycemia in Emerging Adults with Type 1 Diabetes

2019 Bridge to Success Grant for Early Career Investigators

Stephanie Griggs, PhD, RN

Case Western Reserve University

Key Project Outcomes

Type 1 diabetes (T1D) affects approximately 2 million Americans, and only 2 in 8 young adults ages 18-30 years achieve glycemic targets (A1C <7.0%). Not achieving targets increases risk for premature macrovascular (coronary artery disease, peripheral arterial disease, and stroke) and microvascular (retinopathy, nephropathy, neuropathy) complications compared to the general population.  The purpose of this research was to understand the role of the circadian (24-hour) timing system in glucoregulation using actigraphy and continuous glucose monitoring devices over 2-weeks. This is the first study to detect associations between rest-activity rhythms and glucose fluctuations over 2-weeks among young adults with type 1 diabetes. These associations suggest that interventions targeted at improving the stability and strength of the circadian rhythm may improve glucocoregulation and other diabetes outcomes in young adults with T1D. This study informed our development of a cognitive behavioral sleep self-management intervention to extend sleep and improve timing in this high-risk population of young adults with T1D.

Journal Articles

Applied Nursing Research

A systematic review of sleep deprivation and neurobehavioral function in young adults

Behavioral Sleep Medicine

“Feeling Anxious about Catching COVID”: Facilitators and Barriers of Sleep Health among Young Adults with Type 1 Diabetes

Chronobiology International

Circadian characteristics of the rest activity rhythm, executive function, and glucose fluctuations in young adults with type 1 diabetes

Journal of Clinical Endocrinology and Metabolism

Variations in sleep characteristics and glucose regulation in young adults with type 1 diabetes

Journal of Clinical Sleep Medicine

Sleep-wake characteristics, daytime sleepiness, and glycemia in young adults with type 1 diabetes

Journal of Medical Internet Research: Diabetes

Evaluation of Web-Based and In-Person Methods to Recruit Adults With Type 1 Diabetes for a Mobile Exercise Intervention: Prospective Observational Study

Scientific Reports

Glucose and unstructured physical activity coupling during sleep and wake in young adults with type 1 diabetes

The Science of Diabetes Self-Management and Care

Objective Sleep-Wake Characteristics Are Associated With Diabetes Symptoms in Young Adults With Type 1 Diabetes

Western Journal of Nursing Research

Exploring sleep health in young adults with type 1 diabetes

Meeting Abstracts

Sigma International Research Congress

Actigraphy derived sleep-wake characteristics and symptoms in young adults with type 1 diabetes


Rest activity rhythms, symptom burden, and glucose variability in young adults with type 1 diabetes

A Systematic Review of Sleep Health and Outpatient Opioid Use Disorder Treatment in Adults