Sleep Microarchitecture and Daytime Sleepiness in the Sleep Heart Health Study

2020 Bridge to Success Grant for Early Career Investigators

Ankit Parekh, PhD
Icahn School of Medicine at Mount Sinai

Key Project Outcomes

This study shows that the delta bursts following a K-complex in sleep has a protective effect when it comes to all-cause mortality. Using data from over 3900 subjects who were part of the sleep heart health study, we show that the ∆SWAK, a measure of slow-wave/K-complex coupling is associated with all-cause mortality, above and beyond the effect of age, gender and BMI. The findings provide further evidence of the use of sleep EEG micro-architecture in better understanding the consequences of sleep disruption.



Slow wave activity surrounding stage N2 K-complexes is associated with long-term all-cause mortality in a large community-dwelling cohort

Journal Articles

American Journal of Respiratory and Critical Care Medicine

Ventilatory burden as a measure of obstructive sleep apnea severity is predictive of cardiovascular and all-cause mortality